Synthesis of new condensed pyrano[4,3-b]pyridines based on ethyl-3-aminopyrano[4,3-b]thieno[3,2-e]pyridine2-carboxylate derivative

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Resumo

Methods for the synthesis of new fused pyrano[4,3- b ]pyridine derivatives based on the ethyl-3-amino-pyrano[4,3- b ]thieno[3,2- e ]pyridine-2-carboxylate derivative have been developed. The interaction reactions of the condensed 3-(phenoxycarbonyl)-amino derivative with primary and secondary amines have been studied. It has been established that in the case of primary amines, the reaction is accompanied by cyclization with the formation of fused pyrimidines. However, when secondary amines are used, the structure of the final product depends on the reaction conditions. The antibacterial properties of the synthesized compounds were studied.

Sobre autores

V. Dabaeva

Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia

Email: valyа.dabayeva@mail.ru

M. Bagdasaryan

Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia

Email: valyа.dabayeva@mail.ru

E. Paronikyan

Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia

Email: valyа.dabayeva@mail.ru

I. Barkhudaryants

Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia

Email: valyа.dabayeva@mail.ru

G. Panosyan

Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia

Email: valyа.dabayeva@mail.ru

G. Stepanyan

Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia

Email: valyа.dabayeva@mail.ru

Sh. Dashyan

Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia

Email: valyа.dabayeva@mail.ru

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