One-pot synthesis of (E)-3-(N-vinylpyrro-2-yl)acrylic acids

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The paper describes the synthesis of a previously unknown class of N -vinylpyrrolyl acrylic acids - multifunctional monomers and promising building blocks for fine organic synthesis, which was created on the basis of the fundamental works of academician Trofimov B.A., namely the synthesis of an inexhaustible class of N -vinylpyrroles.

作者简介

V. Shcherbakova

A.E. Favorskii Irkutsk institute of chemistry SB RAS

S. Martynovskaya

A.E. Favorskii Irkutsk institute of chemistry SB RAS

E. Gyrgenova

A.E. Favorskii Irkutsk institute of chemistry SB RAS

I. Ushakov

A.E. Favorskii Irkutsk institute of chemistry SB RAS

A. Ivanov

A.E. Favorskii Irkutsk institute of chemistry SB RAS

Email: ivanov@irioch.irk.ru

参考

  1. Roth B.D. Pat. 5273995 (1993). США.
  2. Li J.J., Johnson D.S., Sliskovic D.R., Roth B.D. Contemporary Drug Synthesis. New Jersey: Wiley-Interscience, 2004.
  3. You H., Youn H.-S., Im I., Bae M.-H., Lee S.-K., Ko H., Eom S.H., Kim Y.-Ch. Eur. J. Med. Chem. 2011, 46, 1153-1164. doi: 10.1016/j.ejmech.2011.01.034
  4. Kancharla P., Kelly J.X., Reynolds K.A. J. Med. Chem. 2015, 58, 7286-7309. doi: 10.1021/acs.jmedchem.5b00560
  5. Trofimov B.A., Mikhaleva A.I. Chem. Heterocycl. Compd. 1980, 10, 979-991. doi doi.org/10.1007/BF00496592

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