EXPERIMENTAL STUDIES OF BIOCHEMICAL SYSTEMS OF WHITE RATS WITH FENTANYL ACUTE INTOXICATION

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Experimental studies of the biochemical systems of white outbred rats in a single intoxication with fentanyl have been carried out. It has been established that acute intravenous intoxication with synthetic narcotic analgesics (fentanyl) leads to an intensification of lipid peroxidation processes indicating the development of oxidative stress. The peculiar biochemical changes of acute drug intoxication are revealed. They are represented by certain combinations of impaired biochemical parameters of blood serum.

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D. Gorbunov

Institute of Toxicology of the Federal Medical and Biological Agency.

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192019, Saint-Petersburg. 俄罗斯联邦

L. Erdniev

The 33rd Central Scientific Research Institute, Ministry of Defense of the Russian Federation.

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412918, Volsk-18. 俄罗斯联邦

I. Nelga

The 33rd Central Scientific Research Institute, Ministry of Defense of the Russian Federation.

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412918, Volsk-18. 俄罗斯联邦

I. Medvetsky

The 33rd Central Scientific Research Institute, Ministry of Defense of the Russian Federation.

Email: fake@neicon.ru
412918, Volsk-18. 俄罗斯联邦

A. Mikshta

The 33rd Central Scientific Research Institute, Ministry of Defense of the Russian Federation.

Email: fake@neicon.ru
412918, Volsk-18. 俄罗斯联邦

E. Andreeva

The 33rd Central Scientific Research Institute, Ministry of Defense of the Russian Federation.

Email: fake@neicon.ru
412918, Volsk-18. 俄罗斯联邦

参考

  1. Golikov S.N. General mechanisms of toxic effects. - Moscow: Medicine, 1986. - 264 p. (in Russian)
  2. Kashuro V.A. Glutathione system and lipid peroxide oxidizing in acute severe intoxication caused by cyclophosphan. Сand. med. sci.diss. Saint-Petersburg; 2003. (in Russian)
  3. Afonsky S.I. Biochemistry of animals. - M: “High school”. 1970. - 605 p. (in Russian)
  4. Ovsyannikov M.V., Maslovsky S.L., Milyutina N.P. Structural state of erythrocyte membranes in the pathogenesis of opium addiction. Biological Membranes. - 2005. - Т. 22, №2. - С. 100-104. (in Russian)
  5. Batotsyrenova E.G., Kostrova T.A., Zhilyaeva E.Kh. Kashuro V.A. Changes in the antioxidant system in acute severe poisoning with sodium thiopental in the long term in conditions of desynchronosis. In: Oxidative stress in psychiatry and neurology. Proc. of the all-Rus. conf. with internat. part. 2016, 19-20. (in Russian)
  6. Usmanova N.N. Somatic complications of opium drug addiction in adolescents and the role of free radical processes in their pathogenesis: Author’s abstract. diss. for academic competition. degree of candidate of biological sciences. - M., 2000. - 20 p. (in Russian)
  7. Popov V.F., Tolstikhin O.N. General Ecology. - Yakutsk: Publishing House of Yakut University, 2000. - 150 p. (in Russian)
  8. Serdyukova N.B. Drugs and drug addiction. - Rostov N / A: Phoenix, 2000. - 256 p. (in Russian)
  9. Methodical recommendations. Modeling of intoxications with deprimirating agents and evaluation of the severity of the depressive effect. – M.: FM FMBA of Russia 21.10-13, 2013. - 31 p. (in Russian)
  10. N.A. Loshadkin, B.A. Kurlyandsky, GV Bezhenar, L.V. Daryna Military Toxicology. - M: “Medicine.” 2006. - 207 р. (in Russian)
  11. Kubrikova Yu.V. The activity of catalase and superoxide dismutase in the blood serum of people working under conditions of an increased concentration of metals in the environment [Text] / Yu.V. Kubrikova, TN. Popova, A.V. Makeyeva // The successes of modern natural science. - 2011. - No. 6. - P. 50-51. (in Russian)
  12. Bogacheva E.V. Determination of the concentration of malonic dialdehyde in the blood serum of rats irradiated with an electromagnetic field of a meter range [Text] / E.V. Bogacheva, V.V. Alabovsky, S.Yu. Perov // Proceedings of the Saratov University. New episode. Series Chemistry. Biology. Ecology. - 2016. - P. 12 - 17. (in Russian)
  13. Kashuro V.A., Karpischenko A.I., Novikova T.M., Glushkova T.I., Minaeva L.V., Sibirev S.A. The system state of glutathione in the tissues of the parenchymatous organs of laboratory animals with repeated administration of cyclophosphamide. Nephr. 2006.10(4):82-86. (in Russian)

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