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Synthesis of 6,9-Diaryl-5Н-imidazo[2,1-d][1,2,5]triazepines and Their Dihydro Derivatives
- Authors: Lomov D.A.1
-
Affiliations:
- Litvinenko Institute of Physical Organic and Coal Chemistry
- Issue: Vol 95, No 3-4 (2025)
- Pages: 107-113
- Section: Articles
- URL: https://freezetech.ru/0044-460X/article/view/686601
- DOI: https://doi.org/10.31857/S0044460X25030046
- EDN: https://elibrary.ru/DDBTWW
- ID: 686601
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Abstract
2-(2-Benzoyl-1H-imidazol-1-yl)-1-arylethanones were obtained by alkylation of 2-benzoylimidazole with phenacyl bromides; their cyclization with hydrazine hydrate leads to the formation of previously undescribed 6-aryl-9-phenyl-5H-imidazo[2,1-d][1,2,5]triazepines. The reduction of the latter with sodium borohydride in a dioxane medium leads to the production of 6-aryl-9-phenyl-6,7-dihydro-5H-imidazo[2,1-d][1,2,5]triazepines.
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About the authors
Dmitry A. Lomov
Litvinenko Institute of Physical Organic and Coal Chemistry
Author for correspondence.
Email: lomov_dmitrii@mail.ru
ORCID iD: 0000-0001-9955-6225
Russian Federation, Donetsk
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