ASSESSMENT OF TOXICITY AND HAZARD OF TECHNICAL PRODUCT OF TRIAZINONE’S DERIVATIVE

Мұқаба

Дәйексөз келтіру

Толық мәтін

Аннотация

Experimental assessment of toxicity and hazard of technical product of triazinone’s derivative at its peroral administration into warm-blooded animals’ bodies (male rats) has been conducted to determine the character of the substance biological action. Its acute peroral toxicity was at the level of LD50 -1693 ± 470 mg/kg of body weight, hazard class – 4 according to Hygienic Classification of Pesticides (Sanitary Rules & Standards 1.2.2584-10). Effective dose was 62.5 mg/kg b.w., non-effective dose (NOEL) was 12.5 mg/kg b.w. ADI was 0.1 mg/kg b.w.

Авторлар туралы

V. Rakitskii

F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor

Хат алмасуға жауапты Автор.
Email: pesticidi@yandex.ru

Rakitskii Valery Nikolaevich 

141014, Mytishchi, Moscow Region,

Ресей

T. Еpishina

F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor

Email: pesticidi@yandex.ru

Epishina Tatiana Mihailovna

141014, Mytishchi, Moscow Region,

Ресей

E. Chkhvirkiya

F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor

Email: pesticidi@yandex.ru

Chkhvirkiya Elena Grigor'evna

141014, Mytishchi, Moscow Region,

Ресей

T Sinitskaya

F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor

Email: pesticidi@yandex.ru

Sinitskaya Tat'yana Alekseevna

141014, Mytishchi, Moscow Region,

Ресей

Е. Mukhina

.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor

Email: pesticidi@yandex.ru

Mukhina Ekaterina Aleksandrovna

141014, Mytishchi, Moscow Region,

Ресей

Әдебиет тізімі

  1. Rakitskii V.N. Hygienic principles and criteria of pesticide danger (risk) assessment. In:Collection of Studies: Hygienic Aspects of Environment and Public Health Protection. Sbornik nauchnykh trudov: Gigienicheskie aspekty okhrany okruzhayushchry sredy I zdoron’ya naseleniya. Moscow;1999.(in Russian)
  2. Sinitskaya T.A., Malinovskaya H.H.Toxicological-hygienic justification of the acceptable daily intake of acetamiprid. М. Gigiena and sanitariy. 2016; 95(11):1055-1058.
  3. Methodical instruction on hygienic assessment of new pesticides. Kiev. 1988; 210 p.
  4. Kagan Y.S. General pesticide toxicology. – Kiev. Zdorovie. 1981; 176 р.
  5. Rylova M.L. Method of exploring chronic action of adverse environment factors in theexperiment. L., Medicine.1964; 227 р.
  6. Pavlenko S.M. Application of summation-threshold index in toxicological experiment on white rats. Methodic of sanitary-toxicological experiment: scientific works collections of MNIIG named after F.F.Erisman. M. 1975; 5-
  7. Methodical recommendation on using reaction of animals’ behaviour in toxicological researches for hygienic standartization. Kiev. 1980; 47 p.
  8. Anokhin P.K. Surveys on functional systems physiology.M. Medicine. 1975; 448р.
  9. Clinical biochemistry: Manual for laboratory doctors. Kalb V.G., Kamyshnikov V.S. Minsk, Byelorussia. 1976; 311p.

Қосымша файлдар

Қосымша файлдар
Әрекет
1. JATS XML
Жүктеу

© Rakitskii V.N., Еpishina T.M., Chkhvirkiya E.G., Sinitskaya T.A., Mukhina Е.A., 2019


СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 81728 от 11 декабря 2013.